iTero™ NIRI technology, a proven tool for interproximal caries screening and monitoring.¹

With the iTero Element® 5D Plus Lite to 5D Plus Upgrade Kit, you can activate the scientifically proven technology of NIRI (Near Infra-Red Imaging) for interproximal caries screening and monitoring to access the full potential your existing iTero Element 5D Plus Lite imaging system.

Upgrade your existing iTero Element Plus scanner software and enjoy an eye opening educational tool that will establish patient treatment acceptance, trust, and loyalty.

iTero NIRI technology...

An interproximal caries detection tool you can trust.²

• 66% more sensitive than bite-wing X-ray for proximal lesions detection based on a clinical study for caries detection with the largest amount of analyzed data¹ conducted in real world setting.³

Easy to adopt

• No additional scan, no calibration needed, without harmful radiation

• Powerful patient engagement tool during oral health assessments and hygiene appointments

iTero NIRI technology ROI

• When incorporating iTero NIRI technology into their pictures, surveyed doctors reported that they increased business revenue by 34% ⁴ and treatment acceptance by 71%⁵

What other doctors that upgraded to iTero NIRI technology say

What is included in the NIRI technology Upgrade Kit (U.S. Only)

The package includes:

• Upgrade guide
• New label with your wand's serial number
• Wand barrier sleeves (box of 20)
• Vent cover (quantity of 3)
• iTero Element 5D Plus User Manual (mobile/cart)

The iTero Element 5D Plus imaging system requires the use of a full barrier wand sleeve and clip-on vent cover in the United States. United States Customers must follow the instructions in the 5D Plus Lite to 5D Plus Software Update Guide booklet, including providing photographic evidence of the wand, vent cover, and new label and signing the 5D Plus Upgrade Customer Approval, prior to activation of the NIRI Software Upgrade Package by Align.

1, 2. Based on a multisite clinical study conducted in real-world settings with patients in five clinics across Germany and Canada using iTero NIRI technology (Near Infra-red imaging) (n= 5,796 proximal
tooth surfaces with 3,502 posterior proximal tooth surfaces in 102 patients ) as a tool in aiding in detection and diagnosis of interproximal caries above the gingiva. Study sponsored and financed by
Align Technology, Inc. iTero NIRI technology is only available on iTero Element 5D and iTero Element 5D Plus (excluding Lite software configuration) imaging systems. Data on file at Align Technology,
as of February 10, 2021.
3. Based on a multisite clinical study conducted in real-world settings using iTero NIRI technology (Near Infra-red imaging) (n= 5,796 proximal tooth surfaces with 3,502 posterior proximal tooth
surfaces in 102 patients ) as a tool in aiding in detection and diagnosis of interproximal caries above the gingiva. The largest amount of data refers to the numbers of proximal surfaces included in near
infra-red imaging trials. Accuracy means the % agreement between the diagnoses from the BWX and NIRI, calculated as [Total agreements] / [Total surfaces] % = [56 (true positive) + 3338 (true
negative)] / 3502 = 96.9%. Data on file at Align Technology, as of February 10, 2021.
4. Based on a subset of 59 cases where iTero Element 5D imaging system was compared against the clinical evaluation of posterior proximal carious lesions above the gingiva as observed during caries
debridement, reported as part of a multisite clinical study conducted in real world settings with patients in five clinics across Germany and Canada comparing iTero NIRI technology (Near Infra-red
imaging) of the iTero Element 5D imaging system to bite-wing x-rays (BWX) (n= 3,502 posterior proximal tooth surfaces out of 5,796 proximal surfaces in 102 patients) as a tool in aiding in detection
and diagnosis. Study sponsored and financed by Align Technology, Inc. iTero NIRI technology is only available on iTero Element 5D and iTero Element 5D Plus (excluding Lite software configuration)
imaging systems. Data on file at Align Technology, as of September 2, 2021.
5. Based on a survey in May of 2019 of n = 15 practitioners who participated in a global limited market release, working with iTero Element 5D for an average period of 6 months, representing both GPs and
Orthos in CAN, EU and APAC, who were presented with a level of agreement scale from strongly agree to strongly disagree with the following statement: “Incorporating the iTero Element 5D scanner
into my current diagnostic protocol, I experienced an increase in treated interproximal caries cases on my patients at my practice”, and then asked to estimate the average increase in revenue for the
practice. Data on file at Align Technology, as of November 15, 2019.